ARA-290

ARA-290 | Cibinetide | Innate Repair Receptor Agonist | Research Reference Grade

ARA-290 (cibinetide) is an 11-amino-acid synthetic peptide derived from the helix B surface of erythropoietin (EPO). It was designed to engage the tissue-protective innate repair receptor, a heterocomplex of the EPO receptor and the beta-common receptor (CD131), without engaging the classical EPO receptor pathway associated with erythropoiesis. PerformanceLabsUK supplies it strictly as a research reference material for in vitro laboratory investigation. Researchers must not use ARA-290 for human or veterinary purposes.

Areas of Research Interest

• In particular, researchers study its selective activation of the innate repair receptor (EPOR/CD131) and downstream tissue-protective signalling.
• For example, inflammation research examines its modulation of pro-inflammatory cytokine signalling in cell and tissue models.
• Peripheral nerve research also shows strong interest in this peptide, investigating small-fibre nerve biology in preclinical models.
• Additionally, metabolic research explores its effects on islet cell resilience and glucose-handling pathways in animal models.
• Furthermore, it serves as a reference molecule for separating the tissue-protective actions of EPO from its haematopoietic effects.

Primary Research Areas: Innate Repair Receptor | Tissue Protection | Inflammation Biology | Peripheral Nerve Research | EPO-Derived Peptides

Researchers investigating immune and tissue-repair biology may also wish to review our COA Library for third-party verified analytical data, alongside our related Thymosin Alpha-1 research peptide and KPV research peptide.

REGULATORY NOTICE
FOR LABORATORY RESEARCH USE ONLY, NOT INTENDED FOR HUMAN OR VETERINARY CONSUMPTION

Not a medicinal product, pharmaceutical, food supplement, or cosmetic. Not evaluated or approved by the MHRA, FDA, or any regulatory
authority for use in humans or animals. Must not be used for diagnostic, therapeutic, or preventative purposes.
Must be handled only by qualified professionals within a suitable research environment. By purchasing you confirm research-only use.
Purchasers must be 18+. PerformanceLabsUK accepts no liability for misuse.