PT-141 | Bremelanotide | Melanocortin Receptor Agonist | Research Grade

PT-141 is a cyclic heptapeptide and synthetic analogue of alpha-melanocyte-stimulating hormone (alpha-MSH). PerformanceLabsUK supplies it strictly as a research reference material for in vitro laboratory investigation. Researchers must not use PT-141 for human or veterinary purposes.

In published research, scientists study PT-141 as a non-selective agonist across four melanocortin receptor subtypes: MC1R, MC3R, MC4R, and MC5R. Unlike vascular-acting reference compounds, it draws particular interest from researchers because its proposed mechanism of action operates centrally via hypothalamic melanocortin pathways rather than through peripheral vasodilation. Consequently, it has become a recurring reference compound in central nervous system (CNS) pharmacology literature examining melanocortin receptor signalling cascades.

Research Interest Areas

• Central melanocortin pathway research investigates non-vascular neural signalling mechanisms.
• Melanocortin receptor pharmacology research focuses in particular on MC3R and MC4R activity profiles.
• CNS energy-homeostasis research explores the role of central MC4R signalling in metabolic regulation studies.
• Melanocortin system research also examines downstream G-protein-coupled receptor pathway activation.
• Additionally, comparative neuropeptide chemistry research studies it alongside other alpha-MSH analogues.

Primary Research Areas: Melanocortin Receptor Pharmacology | CNS Signalling | Central Melanocortin Pathway | MC3R/MC4R Research | Neuropeptide Chemistry

PerformanceLabsUK independently tests every PT-141 batch through a third-party laboratory. As a result, we publish a batch-specific Certificate of Analysis in our COA Library. You can also browse our full range of research peptides for related reference materials. For structural and chemical reference data, see the independent PubChem listing.

PERFORMANCELABSUK LTD SUPPLIES 3RD PARTY TESTED RESEARCH REFERENCE MATERIALS FOR IN VITRO LABORATORY INVESTIGATION. WE ARE NOT A PHARMACY, PHARMACEUTICAL COMPANY, OR MEDICAL PROVIDER. ALL PRODUCTS ARE SUPPLIED FOR RESEARCH USE ONLY.