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Research Reference Material

PerformanceLabsUK supplies third party tested research reference peptides and compounds for laboratory investigation into metabolic biology, cellular recovery research, cognitive research, and longevity science.

Retatrutide

Price range: £94.99 through £229.99

Retatrutide is an investigational synthetic peptide. In published laboratory research, it is studied as a single-molecule, multi-receptor agonist at the GLP-1, GIP, and glucagon receptors. The multi-target receptor design is the distinctive feature making it a subject of interest in current metabolic-signalling research. Supplied for in vitro laboratory and scientific research use only, not for human or veterinary use.

Also available in research sets: Metabolic Signalling Pair (Retatrutide + Tesamorelin), The Verified Three (Retatrutide, KLOW + MOTS-c). See all research sets.

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Free UK delivery on orders over £75·£4.99 tracked delivery below that·Order by 12 noon, Monday to Friday, for same-day dispatch

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Every vial ships with a batch-specific certificate of analysis from Janoshik, a third party laboratory, verifiable by task number. If any product fails to match its published certificate, we refund or replace it. That is the whole condition: the certificate, nothing else.

Your statutory rights are unaffected. How to verify a certificate and how the guarantee works.

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  • Batch-specific Certificate of Analysis. Identity by HPLC and mass spectrometry, purity, and a heavy metals panel covering arsenic, cadmium, lead and mercury. How to read one.
  • Reconstitution figures before you order. Work out concentration and withdrawal volume for any vial size and diluent volume with the reconstitution calculator.
  • Supplied for in vitro laboratory and scientific research use only. Not for human or veterinary use. What that means.

Retatrutide | Triple GIP/GLP-1/Glucagon Receptor Agonist | Research Reference Grade

Retatrutide is a single-molecule peptide studied as a triple agonist across the GIP, GLP-1, and glucagon receptors. PerformanceLabsUK supplies it strictly as a research reference material for in vitro laboratory investigation. Researchers must not use Retatrutide for human or veterinary purposes.

In published research, Retatrutide has attracted significant interest for its multi-receptor pharmacology. Specifically, it allows researchers to study simultaneous engagement of incretin and glucagon signalling pathways within a single compound. As a result, it has become a key reference molecule in metabolic-signalling and energy-homeostasis literature.

Areas of Research Interest

  • Researchers study it as a single-molecule triple agonist at GLP-1, GIP, and glucagon receptors.
  • Scientists examine it in receptor pharmacology research for multi-target signalling engagement.
  • Adipose tissue research also explores this peptide, particularly its role in energy-expenditure signalling pathways.
  • Additionally, investigators explore its glucagon receptor pathway engagement and hepatic glucose-regulation signalling.
  • Incretin-pathway research also investigates its metabolic-signalling biology.

Primary Research Areas: Receptor Pharmacology | Incretin Signalling | Energy Expenditure Pathways | Adipose Tissue Biology | Hepatic Glucose Signalling

PerformanceLabsUK has every Retatrutide batch tested by a third-party laboratory. A batch-specific Certificate of Analysis is available on request and will be published in our COA Library. You can also browse our full peptide research range for related reference materials. For structural and chemical reference data, see the independent PubChem listing.

 

REGULATORY NOTICE
FOR LABORATORY RESEARCH USE ONLY, NOT INTENDED FOR HUMAN OR VETERINARY CONSUMPTION

Not a medicinal product, pharmaceutical, food supplement, or cosmetic. Not evaluated or approved by the MHRA, FDA, or any regulatory
authority for use in humans or animals. Must not be used for diagnostic, therapeutic, or preventative purposes.
Must be handled only by qualified professionals within a suitable research environment. By purchasing you confirm research-only use.
Purchasers must be 18+. PerformanceLabsUK accepts no liability for misuse.

Further reading: Retatrutide: Triple Receptor Agonist Research Overview, and Retatrutide vs Tirzepatide: Comparing the Research.

Retatrutide specifications

Research code LY3437943
Class Triple GIP / GLP-1 / glucagon receptor agonist peptide
Molecular weight approx. 4731 g/mol
CAS number 2381089-83-2
Form Lyophilised powder
Vial sizes 10mg, 20mg, 30mg and 40mg (see options above)
Intended use In vitro laboratory research only

Retatrutide vs Tirzepatide vs Semaglutide

The three compounds differ in how many receptors they act on. Semaglutide is a single GLP-1 receptor agonist. Tirzepatide is a dual agonist of the GIP and GLP-1 receptors. Retatrutide adds a third target, the glucagon receptor, making it a triple agonist. This is why Retatrutide is used as a reference molecule for studying combined incretin and glucagon signalling in a single compound. For a deeper look, read Retatrutide vs Tirzepatide: Comparing the Research.

Storage and reconstitution

Store lyophilised Retatrutide at -20°C for long-term storage, or at 2–8°C for short-term storage, away from light and moisture. In the laboratory it is typically reconstituted with bacteriostatic water; our peptide reconstitution calculator works out the volume needed for a target concentration. Once reconstituted, keep refrigerated at 2–8°C and avoid repeated freeze-thaw cycles.

Batch documentation

Batch documentation is available on request, and published certificates of analysis are listed in our COA Library.

Retatrutide FAQ

Where can I buy Retatrutide in the UK?

PerformanceLabsUK supplies Retatrutide in the UK as a research reference material in 10mg, 20mg, 30mg and 40mg vials, dispatched by Royal Mail next-day. It is sold for in vitro laboratory research only and is not for human or veterinary use.

What is the difference between Retatrutide and Tirzepatide?

Tirzepatide acts on two receptors (GIP and GLP-1). Retatrutide acts on three (GIP, GLP-1 and glucagon).

How should Retatrutide be stored?

Keep the lyophilised powder frozen at -20°C for long-term storage. After reconstitution, store at 2–8°C and avoid repeated freeze-thaw cycles.

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Research Resources

Learn more about the science and laboratory context in our Education Hub. For UK dispatch information see Shipping & Delivery. For order policy visit Refunds & Returns or our FAQ. Questions? Contact PerformanceLabsUK.

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