PerformanceLabsUK supplies third party tested research reference peptides and compounds for laboratory investigation into metabolic biology, cellular recovery research, cognitive research, and longevity science.
£94.99 – £229.99Price range: £94.99 through £229.99
Retatrutide is an investigational synthetic peptide. In published laboratory research, it is studied as a single-molecule, multi-receptor agonist at the GLP-1, GIP, and glucagon receptors. The multi-target receptor design is the distinctive feature making it a subject of interest in current metabolic-signalling research. Supplied for in vitro laboratory and scientific research use only, not for human or veterinary use.
Also available in research sets: Metabolic Signalling Pair (Retatrutide + Tesamorelin), The Verified Three (Retatrutide, KLOW + MOTS-c). See all research sets.
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Retatrutide is a single-molecule peptide studied as a triple agonist across the GIP, GLP-1, and glucagon receptors. PerformanceLabsUK supplies it strictly as a research reference material for in vitro laboratory investigation. Researchers must not use Retatrutide for human or veterinary purposes.
In published research, Retatrutide has attracted significant interest for its multi-receptor pharmacology. Specifically, it allows researchers to study simultaneous engagement of incretin and glucagon signalling pathways within a single compound. As a result, it has become a key reference molecule in metabolic-signalling and energy-homeostasis literature.
Primary Research Areas: Receptor Pharmacology | Incretin Signalling | Energy Expenditure Pathways | Adipose Tissue Biology | Hepatic Glucose Signalling
PerformanceLabsUK has every Retatrutide batch tested by a third-party laboratory. A batch-specific Certificate of Analysis is available on request and will be published in our COA Library. You can also browse our full peptide research range for related reference materials. For structural and chemical reference data, see the independent PubChem listing.
REGULATORY NOTICE
FOR LABORATORY RESEARCH USE ONLY, NOT INTENDED FOR HUMAN OR VETERINARY CONSUMPTION
Not a medicinal product, pharmaceutical, food supplement, or cosmetic. Not evaluated or approved by the MHRA, FDA, or any regulatory
authority for use in humans or animals. Must not be used for diagnostic, therapeutic, or preventative purposes.
Must be handled only by qualified professionals within a suitable research environment. By purchasing you confirm research-only use.
Purchasers must be 18+. PerformanceLabsUK accepts no liability for misuse.
Further reading: Retatrutide: Triple Receptor Agonist Research Overview, and Retatrutide vs Tirzepatide: Comparing the Research.
| Research code | LY3437943 |
| Class | Triple GIP / GLP-1 / glucagon receptor agonist peptide |
| Molecular weight | approx. 4731 g/mol |
| CAS number | 2381089-83-2 |
| Form | Lyophilised powder |
| Vial sizes | 10mg, 20mg, 30mg and 40mg (see options above) |
| Intended use | In vitro laboratory research only |
The three compounds differ in how many receptors they act on. Semaglutide is a single GLP-1 receptor agonist. Tirzepatide is a dual agonist of the GIP and GLP-1 receptors. Retatrutide adds a third target, the glucagon receptor, making it a triple agonist. This is why Retatrutide is used as a reference molecule for studying combined incretin and glucagon signalling in a single compound. For a deeper look, read Retatrutide vs Tirzepatide: Comparing the Research.
Store lyophilised Retatrutide at -20°C for long-term storage, or at 2–8°C for short-term storage, away from light and moisture. In the laboratory it is typically reconstituted with bacteriostatic water; our peptide reconstitution calculator works out the volume needed for a target concentration. Once reconstituted, keep refrigerated at 2–8°C and avoid repeated freeze-thaw cycles.
Batch documentation is available on request, and published certificates of analysis are listed in our COA Library.
PerformanceLabsUK supplies Retatrutide in the UK as a research reference material in 10mg, 20mg, 30mg and 40mg vials, dispatched by Royal Mail next-day. It is sold for in vitro laboratory research only and is not for human or veterinary use.
Tirzepatide acts on two receptors (GIP and GLP-1). Retatrutide acts on three (GIP, GLP-1 and glucagon).
Keep the lyophilised powder frozen at -20°C for long-term storage. After reconstitution, store at 2–8°C and avoid repeated freeze-thaw cycles.
Learn more about the science and laboratory context in our Education Hub. For UK dispatch information see Shipping & Delivery. For order policy visit Refunds & Returns or our FAQ. Questions? Contact PerformanceLabsUK.

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All products are supplied strictly for in vitro laboratory research use. Not for human or veterinary consumption.
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