Tirzepatide

Tirzepatide | Dual GIP/GLP-1 Receptor Agonist | Research Reference Grade

Tirzepatide is a single-molecule synthetic peptide studied as a dual agonist at the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. PerformanceLabsUK supplies it strictly as a research reference material for in vitro laboratory investigation. Researchers must not use Tirzepatide for human or veterinary purposes.

In published research, Tirzepatide is one of the most widely referenced incretin-pathway molecules. Its 39-amino-acid sequence is based on the native GIP backbone, with a C20 fatty diacid moiety that supports albumin binding. As a result, it has become a key reference compound in incretin receptor pharmacology and metabolic-signalling literature.

Areas of Research Interest

• Researchers study it as a single-molecule dual agonist at the GIP and GLP-1 receptors.
• Scientists examine its imbalanced receptor profile, with greater relative activity at the GIP receptor, in receptor pharmacology research.
• Signalling research investigates biased agonism at the GLP-1 receptor, including cAMP generation relative to beta-arrestin recruitment.
• Additionally, comparative studies use it alongside single-receptor GLP-1 agonists and the triple agonist Retatrutide to explore multi-receptor incretin pharmacology.
• Furthermore, its acylated structure makes it a useful reference for research into peptide half-life extension through albumin binding.

Primary Research Areas: Incretin Biology | GIP/GLP-1 Receptor Pharmacology | Metabolic Signalling | Biased Agonism | Peptide Half-Life Research

Researchers investigating incretin and metabolic biology may also wish to review our COA Library for third-party verified analytical data, alongside our related Retatrutide research peptide.

REGULATORY NOTICE
FOR LABORATORY RESEARCH USE ONLY, NOT INTENDED FOR HUMAN OR VETERINARY CONSUMPTION

Not a medicinal product, pharmaceutical, food supplement, or cosmetic. Not evaluated or approved by the MHRA, FDA, or any regulatory
authority for use in humans or animals. Must not be used for diagnostic, therapeutic, or preventative purposes.
Must be handled only by qualified professionals within a suitable research environment. By purchasing you confirm research-only use.
Purchasers must be 18+. PerformanceLabsUK accepts no liability for misuse.